Desantis first win came on her own home turf. Having played for three years, wherof a lot at Borgata, she managed to come out on top of the 2006 Borgata Poker Open Ladies' event. She was prepared, saying: "The competition was good, especially at the final table but it was nothing like playing with the big boys downstairs in the Borgata poker room." and summing it up by: "My experience playing with top amateurs and pros prepared me to win the ladies event."